The CCDC53 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to WASHC3. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The CCDC53 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor(NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting(PubMed:19922875, PubMed:20498093)